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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4de184e66796785cf02b53fd0a49bbd1bc146c2faa7f4f3312a3bd05f1e3afb0' 
  AND token = 'A4DC8NQSM7SBBVAdt1u6BuBhCWzehFHIPsdiXWP2tK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}