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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f5403aefc1c4a6a3f539b5daea7211a23aefe63fcb70ca31fcfdb6b6f2de4a59' 
  AND token = '9yudlB6mDV+HgG+REA3lmvwTsHZ3jTN3lmf/2ijfM3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}