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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6d3773e708631bb556f9a6bcaab091a89fb68779f3deead58e1b9bd7fecdf321' 
  AND token = 'LQ7iddcp4vXB0lYvjAINaNoh/slIPy8eoJRlUPmijXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}