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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5d224c0dbf40c399ee6942029bc34cd495998391c3964675aa0d6d0b3c13c1da' 
  AND token = 'HRt17DaexRjBJ6eraCbtgxKUAVP1MihOdGfA8ijycu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}