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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7c645cbbcba448116f92e19e2a7c89771430f28dd51c145de39b3c20df4a29b1' 
  AND token = 'kjM96ZFXmaglZ4IsiCmbWZGWs7AX4m+fuJZxxVi4k8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}