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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '60622a0c4ad663a31e356479e7be7ee2f3b0f58c4b76a63d452113251a3427ac' 
  AND token = '8nOVSQ2+NqBQALkAID8apclL5NVa8DcusQYkPADs92I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}