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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '18e5232aef19c3a3b7dbf4a1120ca7c132978bf7c1617c51b9a63f78131fad64' 
  AND token = 'wD4DOaP8yWgLQ3Ibgq8zBsgzyl8jkcrxWsGGx5ad7iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}