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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0a65f35e33abef88daf478076338c91c2bd186848e941851b3e1f30cdf36d213' 
  AND token = 'N8CU8xnTahFtQGICm8/RP4xUfKdGeF8D4OW9cTSnwO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}