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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2a563fdde79e4be55c6b612a9a3cc47df7adbf95b98f91b750af587699485065' 
  AND token = 'OXsgS3QGlcV/FvNNpOsafG0w2vi7SN7pzuyejxfjF2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}