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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'dbee88bbd6117a08e1e98f311b42367e05acc804050ff4e333e191e7214f3278' 
  AND token = 'D3dAAsmytvw0gtPJyQtFJ6daiz0/Jrd+4z3EjqjqkDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}