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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '18e8cc267657fd89fa120bdb71aa640665d3ec431e6b811b34b0b423643d655c' 
  AND token = '+6vMfMsSekwMdRi+bCLcfATn2g/FV3WCIH19bdir/o0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}