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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b22c0b94f0846941e816703763f2b712411afbb1e1cf8fd9eb96e53dcc55c331' 
  AND token = 'iVPEJY0xtafQO2gY+dpWXRM6XeNPYbiay4/8mIfNJoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}