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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8c9b246732899b049578e50594886c64c834c8edc8ffc4fbdca904449c133e91' 
  AND token = 'F7zhymPkqT8WTeBY74i8+G+pDC7v0u9+Jmmhnv5pm70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}