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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd10bcb59e72ec75670ecd981d03273c2b25b7b47d347ab55dc26132756791978' 
  AND token = 'ZGGCDeGNf4NzCiNER0QZmsBPDicAKsNBT0rIbw7hC8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}