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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8b7a0ffcfd4fc847132a1920b63d6466f7e5734f24333bcfaa9ad88e09644a63' 
  AND token = 'jE11Tmucqa1EmKr3ragVs5j50uO4bPE3Zym9CMe5eKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}