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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '22b97875c85ce671dc1403637ef4d8949c0bbf501e48e4aa046b3cf7e80ebfa5' 
  AND token = 'dbST80EIVkt3o6/9RV0faQroLMXTbUhTI63PIeEgGTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}