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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bee61b96a7492988061ade4df7b429d697d50b50e7c2f321e0065c7a2f27f624' 
  AND token = 'iB2OeGlskIsxlYT7wwd1cYT8LseUGJ46e21pEPW36TU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}