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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '0580e23cb19c086061f7ca3e45746806425267e777cb6215c19a988e757b23f8' 
  AND token = 'maNFr/B2XZQJFCa2eY9VZAfb8OWu51uZ50n9ofhkIWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}