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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '48e731fe7976ba6cf298130f2535422a2dc0d0692d9cd188a8dbfed9f11e085a' 
  AND token = 'qt7D3XI67vSYsVbIe07Mtwe6eXnS5AvJqGIOXFxdhEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}