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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6e94e123f8457279574aeaa4474180cf1805b5b13252d968cc673a40f97050c9' 
  AND token = 'HxW2sb84t5fDNpoSQN/pzY+7QNyz63G0zY4zbcl2V+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}