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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4a40b4607f1330c925382976f2bfdce861f6eb1a8471f4cd6397aab4c49e3351' 
  AND token = 'zvbN9fiyjqi3x7VEf8xs9tFO1WwgGptG2dR45XNZjX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}