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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'bfaf0c36b5525ab8eac3da081d98bd2249f59bd67aa068e6226c0770de686340' 
  AND token = 'XnFW1VELGlBFTcgkdFtfvyypeB7VbfHMrnhjUESUf0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}