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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '39b34c745752c61268369b8abee9532681968029c9e35d0e2080d4912b56360a' 
  AND token = 'SyeeQ23kmwwaqGH6W8DbHpN0j9UvTXjiiRzPoylXmTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}