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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '556351aa24fee364ee7e80d719d827e4b9fc85e64445ea431f5cc28d2f31e470' 
  AND token = 'IlVKTVJm0rWL3ZwFUkbcdIckVYauqahjIUocwRQj3Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}