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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '74fd7a57a14733e0cfe57e9fe61c8aa9043df1edf81412960ace42de3fd0cdfa' 
  AND token = 'BMiPfSDAmn8VvyCPMkczY4zWkqx6BNHT5NhjOeK1wK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}