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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4cc502af11dbce15c31176fe5f37e61802850330eb266f01e6b342c37b85d1f8' 
  AND token = 'hwEcXR7kRnzKwFtlVmsFT7ze4NUw/TSKkILe6Wsfo3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}