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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '998110eb5390b8d5dad7724f1adfc01008b05df0046001185ad6051cd2dab105' 
  AND token = 'qCOWWnniSNpmwmh5MKCoL5x+a/vxSVBsF0kH4zUET5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}