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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5096e0da34ea0913e1370d94d4d300e7841b913049cd9372738b81e1bebab156' 
  AND token = 'opVWqeeG76RnFqeiFQeg+rqUQ5A2SS6ySTfWy2CkCFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}