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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '124522bfbf6a4307071c633c1f46c22da55307c5e869d44480df069fb82900ac' 
  AND token = '4FMuxwIrYkT4+czwb3bWlZFzTzncfTE9F/3yBrN/SIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}