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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5224422ae189b2e1b89993b42b6709fc0423a3b712ae1ee4a1089b48ffeebfbe' 
  AND token = '9hE3Py7fDTovRS8GAd4zDC2TvIYcIuM+oMJd+8ADUTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}