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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '59580319ebf7a1e7a112e1cedb91af2b32c5905e6ee5a46cdd274c6627c07770' 
  AND token = 'sHFfmJNhO1SW/i6o3DrbcFcUlWIIxcW/5UQReQZyAeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}