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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4bd25d4b316b43a2e3bfb3a6050eb7af2e2e7d57ffc4e007d66813a974f1cf4a' 
  AND token = 'VVx1R9/9EEwc3aXw4Oix3VtSitZZssiNVHmbOpH17xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}