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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '291a395103bdbef02438cd450aac9af61e510a2d5fc4f0d4a1944622cca5cc0f' 
  AND token = 'avugIWU4wPfYVeCqd5B389jJMlwgaAfulT9r57a3HCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}