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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c7378d8cfc90149afa5d089cd441b6801d25381abf33fd3deadd3a9c02075616' 
  AND token = '3oO0gydrHJjCM5QOFfDhXuh7ONhaixYlw3fQqcSQ0js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}