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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '65ecb9cd59cafa4e64e62272ce410d8e0614e47e91cd3043550090befad48b2a' 
  AND token = 'HbSxzR8x21miAc6echb0t5DOf3rtAxMRbbvXcXD4xTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}