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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4b1ffee55183bc0d36c09121341995335f18a7e46dab677377fd924a6a04dd7c' 
  AND token = '6hTtR0ltmxtb+oVGtltx4xECvuoQCitNKJByx6xe500=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}