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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a197807b79696260f2205c50e7d3928524562550c6c1ee7fa235191c520c80c6' 
  AND token = 'O6vIM15v2HBgeZdbSvfhEJRayh66NA9LaoTvkiQs9Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}