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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '457f360ae72f4ce2a0c21cf55f85729b1fa669d5dea27f40bd51499c5c1f3a0d' 
  AND token = 'i6AXydVAdKqzNMWls3DvVTkTKr6xxuTARk0Rv4jGZ5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}