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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '43331d267a4c639b64ba0405b7f0175ce18f7364fa1bf9e6d12cd171c64d49fc' 
  AND token = '+jyOAtbNY7PXigkN3WjXT+vsjLatAoE7QdFjo+2HvH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}