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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '725389201222fb82c1aafa253b85d2fb0e41fc68f5b07338be22f66313eaafc9' 
  AND token = 'YpLplNtmisEd0uJK6b1LIMiZi6H8yM8xQnfZkJpd/gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}