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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b15a20a936f84fbb33fc59c88727c15c29fb8c109be2e7187e5697a3b4e630fc' 
  AND token = 'YR2xWyqCuOLM23uK50fy10Y2Vrs4k00MRzbGBTAi2+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}