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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '455af708293f1f470b75c2ca9abcb0736a83c7f75a15906a482b3fbb4a1bdac9' 
  AND token = 'yMTqv82+eNNIy0L4+cWQp0kwtQKkvlTfUcbB4LMPa8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}