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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '16f2b443715661fddc157ab129661ff1523daeafd287ffe7e44c6396f1081af5' 
  AND token = 'z0Tceib1R5JDhXWBHZ+Ml472qO0LigNqVBcpoRq3n0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}