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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1fa125da13b95717c7b4eedab0ad2f21f5806f03132061656fddc9de925c284a' 
  AND token = 'vRYOeSSB8g0aVrPG7UlGkFySaB6qEfYURdvI3cM4oEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}