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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aa1141a9889781b4ac599a5f542fc119231a16e2658df486c4696cbc10d5abca' 
  AND token = 'F4/Qi0tM72w3kkrBCAsSvftE0HSPRFX60/kBZCR+Bxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}