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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5b78c140e7b2b9f1165fbcb10e0d2e393b5c8c54dfe541bf014c9da3da85b2a3' 
  AND token = 'PzDx9AU0c6Mru+u2RGh7YdFDRfxDtf23GpOl5bQQBYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}