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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b225f405a69b6b55121292bcc80f8d792e4173afa6b27d9cf41d48e23ebb4256' 
  AND token = 'TcUeTUUpCUzlSand4p8vmgqFxyw+pptDlcbD5CLISLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}