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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b8635881bdb434e4a06e3f3324a4ab0a99600bc926e90869946a20911865d9f2' 
  AND token = 'YWCdnMTUYp+QW5e/rBy1QkXKZcJNb/yMNxWmxxhT8ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}