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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '181e2d22f96f1463d72b0fd7a4a8013316ca5c0b4f67feda767acaa2dd3da264' 
  AND token = 'yGriFozjESLfHSfGNHtYxmRfM0hnzU2mmIFenSVUI2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}