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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5490603313f6fc84bae9cf264f84b8b7a18da476675b75cd0733b5e9547d7bfd' 
  AND token = '9LK9S75WL6sKnkJFsrCDVp5EKVZ8B7a/RNCwG27TpCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}